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Rheumatoid Arthritis Offspring Show Normal School Performance

Aug 02, 2021 12:14 pm

A prospective, longitudinal study of the cognitive development of children born to mothers with rheumatoid arthritis (RA) demonstrates normal development as measured by comparative school test scores.

This study included Danish children born 1995–2008 (n=934) and compared to non-RA children listed in the National School Test Register (n = 738,862). Reading and math results were included (reading: grades 2, 4, 6, and 8;  math:grades 3 and 6).

Overall, they found no differences in reading test scores between maternal RA exposed and unexposed children.

RA exposed children scored s;ightly lower in mathematics tests (adjusted differences of mean score –0.14 SD (95% confidence interval [95% CI] –0.23, –0.06) and –0.16 SD (95% CI –0.26, –0.07).

Children exposed to preclinical RA (n = 589) showed the same performance as children exposed to RA.

These results do not suggest that RA in pregnancy has a significant developmental impact on offspring as measured in later years by school performance.

The author has no conflicts of interest to disclose related to this subject

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