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B-Cell Stimulating Factors Tied to Lymphoma in Sjogren's

MedPage Today

Genetic blood tests indicated that Bruton's tyrosine kinase (BTK) and a cytokine called APRIL were overexpressed in patients with primary Sjögren's syndrome who subsequently developed lymphoma, French researchers reported, suggesting that BTK inhibitors might be useful in this population.

ICYMI: Psoriatic Arthritis and Pregnancy

Dr. Christina Chambers, an epidemiologist at the University of California San Diego and the principal investigator of MotherToBaby Pregnancy Studies, reviewed the available data on psoriatic arthritis and pregnancy. There is little evidence at this time that pregnancy affects PsA, though studies reliably demonstrate increase in disease activity in the post-partum period in both skin and joint disease.

One in Ten has Autoimmune Disease

A UK population-based study suggests that autoimmune diseases affect approximately one in ten individuals.

RNL23 Replays (5.6.2023)

This week on the podcast we feature replay content from RNL 2023, cannabis effects on pain and sleep, and what drives PJP risk the most - steroids or RTX?

Prevalence and Mortality of IgG4-related disease in the USA

A current review of the epidemiology of IgG4-related disease (IgG4-RD) in the USA shows a low prevalence with possibly increasing numbers, owing to increasing awareness of this unique immune-mediated condition.

Romosuzumab and Low Sclerostin Levels Underlie CV Risk

EurekAlert!

New research highlights potential safety concerns around women taking romosozumab, a new anti-osteoporosis drug available on the NHS.

Lupus During Pregnancy Carries Higher Maternal, Fetal Morbidity Risks

MedPage Today

Women with systemic lupus erythematosus (SLE) had higher risks for maternal and fetal morbidity compared to those without the chronic autoimmune disorder, according to a nationwide analysis of U.S. data.

Pericarditis Management

On the final day of ACR 2023 State of the Art Conference, Dr. Paul Cremer reviewed pericarditis management. Dr. Cremer, a cardiologist at the Cleveland Clinic Foundation, reviewed the questions patients ask about pericarditis including why the disease develops, will it recur, how is it treated, and what will their treatment duration be. 

Treatment and Management of Neuropsychiatric Lupus

On the first day of ACR State of the Art conference in Orlando, Florida, Dr. Michelle Petri reviewed the treatment and management of neuropsychiatric lupus. Dr. Petri, a lupus expert from Johns Hopkins Rheumatology, reviewed the latest clinical and animal model studies that offer hope in treatment and gave wide-ranging pearls on a variety of issues that can be faced in this disorder. 

ACR 2023 Convergence Brings Back the Poster Hall and 4 Day Meeting

ACR

ACR Convergence 2023, the annual meeting of the American College of Rheumatology (ACR) and the world’s premier rheumatology experience, will be held Nov. 10 – 15 at the San Diego Convention Center in San Diego, CA.

ICYMI: What to do about pre-clinical RA?

RheumNow Live’s 2023 conference led with this year’s hot topic of rheumatoid arthritis, especially what to do regarding pre-clinical RA. Dr. Kevin Deane started the discussion by mapping out a very complex course of RA, beginning with a person’s genetic and environmental risk factors. What are Dr. Deane’s recommendations for management of pre-RA patients?

PJP Prophylaxis Needed with Steroids and Rituximab

Pneumocystis jirovecii pneumonia (PJP) can be a life-threatening infection in immunocompromised patients. The 2023 EULAR Vasculitis guidelines recommends primary prophylaxis with antibiotics, especially in rheumatic disease patients receiving rituximab (RTX).

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