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Clinical Skills

Outpatient Visits Return to Pre-COVID Rates

Oct 19, 2020

The COVID-19 pandemic dramatically impacted outpatient care - numbers, scope, quality, etc, but a recent study suggests that while COVID has changed the scope of care, the numbers of outpatient visits have risen to near pre-pandemic numbers.

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ICI Arthritis Tied to Cancer Progression

Oct 14, 2020

Cancer patients treated with immune checkpoint inhibitors (ICI) who develop severe arthritis may be at risk for progression of the malignancy, a single-center study suggested.



Almost 90% of patients treated with ICI develop immune-related adverse events, which can include pulmonary,

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RheumNow Podcast – Bad Disease & Bad Outcomes (10.9.20)

Oct 08, 2020

Dr. Jack Cush Reviews the news and journal articles from the past week on RheumNow.com.

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RheumNow Podcast – Function Follows Form (10.2.20)

Oct 01, 2020

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com. Regulatory approvals, update on global rheumatology alliance, smoking and psoriasis, gabapentin let down and defining difficult RA.

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Defining Difficult Rheumatoid Arthritis

Oct 01, 2020

‘Difficult-to-treat RA’ is an oft-used term that carries various clinical qualities and therapeutic disappointments. A EULAR Task Force was established to develop recommendations for the management of difficult-to-treat rheumatoid arthritis and as a first step, have put forth their definition of

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Insights into Antinuclear Antibodies in Systemic Lupus Erythematosus

Sep 03, 2020

Pisetsky and Lipsky have reviewed the evolving literature on the utility of antinuclear antibodies (ANA). ANAs generated as part of an autoimmune disorder may form immune complexes that mediate pathogenesis by tissue deposition or cytokine induction.



ANAs are directed at DNA or

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Hepatitis C Anti-Viral Drug-Induced Arthritis

Aug 27, 2020

Curative direct-acting antiviral therapy (DAAT) for hepatitis-C virus (HCV) infection has been revolutionary, but a novel report shows that nearly one quarter of DAAT treated patients developed new onset or significant worsening of MSK symptoms, despite being negative for hepatitis-C by PCR

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In Lupus, Older Age and Male Sex Raise Cancer Risk

Aug 25, 2020

Among patients with systemic lupus erythematosus (SLE), cancer risks overall were associated with older age at diagnosis and male sex, and lung cancer specifically was related to smoking, analysis of data from a large multicenter cohort found.

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Diagnostic Accuracy of Symptoms, Signs and Labs in GCA

Aug 23, 2020

A systematic review and meta-analysis of 68 diagnostic cohort studies (14 037 patients) suggests that no one feature is more impactful that the combination of symptoms, signs, and laboratory tests to diagnose the presence giant cell arteritis (GCA).



From these analyses findings

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Selective Biologic Responses in Seropositive RA

Aug 20, 2020

The Journal of Rheuatology reports a pooled analysis of patients from 16 observational RA registries that examined the association between seropositivity (RF or ACPA) with biologic DMARDs responses; they showed better clinical responses when seropositive RA patients receive abatacept (ABA) or

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RheumNow Podcast – The Bad News That’s Fit to Print (8.21.20)

Aug 20, 2020

Dr Jack Cush reviews the news and journal reports from the past week on RheumNow: filgotinib rejection, delays in diagnosis, metformin benefits COVID, Abx and IBD, and UPA beats MTX.

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Are Women in Rheumatology Closing the Gap?

Aug 20, 2020

"Fierce, Formidable and Phenomenal" was the tag line used to introduce Vice-Presidential candidate, Kamala Harris. Her introduction followed a review of the increasing role of women in voting, society and politics in America. Has the same been realized by women in academic medicine and

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New Criteria for Discoid Lupus

Aug 19, 2020

JAMA Dermatology has proposed an initial validation of classification criteria for discoid lupus erythematosus (DLE), primarily for research purposes, but with clinical applicatility.



Candidate criteria were prospectively develped in 215 DLE patients from international

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Check out my Virtual Video Exam - 5 minutes of a combo of Simon Sez and the Macarena hits the high points of a functional virtual examination. https://t.co/iwHTJKQtEC

Dr. John Cush RheumNow ( View Tweet)

Aug 14, 2020

RheumNow Podcast - The SARS-CoV-2 Update (8-14-20)

Aug 14, 2020

Dr. Jack Cush updates the news and journal articles from the past week on RheumNow.com, with information on enthesitis, nr-Ax-SpA, UAB, Blockbuster Rheum Drugs and use of ACE inhibitors.

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Study of 181 elderly pts with knee osteoarthritis: Kellgren-Lawrence scores were not associated w/ depression, cognitive loss, QOL, but higher KL 2-4 were assoc w/ the worst WOMAC scores and risk of falls.

Dr. John Cush RheumNow ( View Tweet)

Aug 14, 2020
Correlation study of MRI and OA features finds meniscal extrusion, full thickness cartilage loss and osteophytes were associated with clinical knee pain.

Dr. John Cush RheumNow ( View Tweet)

Aug 10, 2020

RheumNow Podcast – Why Do We Love Rheumatology Fellows? (8.7.20)

Aug 06, 2020

Dr. Jack Cush reviews why we all love our rheumatology fellows and our best advice for them stemming from these articles.

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Wearable Technology to Measure Arthritis Outcomes

Aug 04, 2020

In this lockdown, virtual medicine, post-COVID world, wouldn't it be ideal to have an reliable digital readout on patient activity as a measure of health? A multicenter study from the University of Nebraska Medical Center and the University of Alabama at Birminghams have completed a novel

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Analysis of administrative health data (1984‐2016) on 12984 #RA pts shows RA w/ psychiatric comorbidities (depression, anxiety, bipolar, schizophrenia) had more additive visits (10.9), hospitalizations, hospital days (3.6), more drugs (7.3) & FP visits https://t

Dr. John Cush RheumNow ( View Tweet)

Jul 29, 2020

PRIME Cells Predicting Rheumatoid Arthritis Flares

Jul 16, 2020

The current issue of NEJM reports a novel cell type that may be used to identify rheumatoid arthritis (RA) patients who may flare. 

Investigators prospectively collected blood samples from 4 patients for longitudinal RNA sequencing (RNA-seq) for discovery of moleculartranscripts that were

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Canadian 1484 incident early #RA pts (enrolled 2007–2017). SC MTX monotherapy had fewer Rx changes(45% SC vs 79% PO)with longer treatment duration. Similarly taking biologics or triple therapy had a longer time without treatment change. https://t.co/babj1MvTNB

Dr. John Cush RheumNow ( View Tweet)

Jul 15, 2020
Best advice by Dr. R Landewe @EULAR2020 "Do NOT lose contact with your patients during the pandemic!" Many patients are fearful and will not reach out to their physicians; don't let them get lost in the shuffle. @rheumnow https://t.co/FAkEYexsGo
Jun 05, 2020

Systemic Sclerosis Future Therapies and Outcome Measures

May 19, 2020

Nagaraja, Khanna and colleagues have published an overview of current and future therapies in patients with systemic sclerosis (SSc) and have reviewed the potential outcome measures for this difficult autoimmune disorder. Notably there have been several novel agents studied in recent years,

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Interview w/ Private Practice Rheums on Covid - Drs. Herb Baraf and Danny Ricciardi. DC & Brooklyn Docs wrangle technology, Telehealth, Return to normal, the future and more.

Dr. John Cush RheumNow ( View Tweet)

May 13, 2020
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