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Drugs that May Induce Raynaud's
A systematic review by Khouri examined the extent drugs are capable of inducing Raynaud's phenomenon (RP).
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Pregnancies are Adversely Affected Even Before the Diagnosis of Lupus
Arkema and colleagues assessed maternal and fetal outcomes in patients with SLE, pre-clinical (prior to onset) SLE and prevalent maternal SLE during pregnancy compared with the general population.
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Zika Virus May Cause Guillain-Barré Syndrome
The spectrum and extent of the Zika virus is still evolving. Lancet has reported 42 patients diagnosed with Guillain-Barré syndrome (GBS) during the Zika virus outbreak in French Polynesia.
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Subclinical Synovitis in Psoriasis Portends Future Psoriatic Arthritis
It is estimated that nearly 30% of psoriasis patients will develop psoriatic arthritis (PsA). This prevalence was studied by performing MRI scans on asymptomatic psoriasis (n=56) and 30 control patients without arthritis.
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Challenges of Dermatomyositis Progress
In the current issue of Lancet, Pierre Miossec discusses the challenges of studying and managing juvenile dermatomyositis and, specifically, the
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Pulmonary Hypertension Earlier and More Severe in Men with Scleroderma
Pulmonary hypertension is an uncommon complication of systemic sclerosis (SSc) and historically thought to slowly evolve in those with limited scleroderma over many years.
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CBC Hidden Pearls
CBC…it’s easy as 123! The complete blood count (aka, CBC) is the most routine, but indispensable, of all medical assessments.
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Lupus Flares After Renal Transplant
Whether lupus activity is ameliorated by end-stage renal disease (ESRD) or transplantation has been debated.
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RWCS 2016 - Updates in AS, PsA and Lupus
Update on Ankylosing Spondylitis and Spondyloarthritis
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Young Lupus Patients Have Higher Mortality Risk
A retrospective study examined mortality rates by comparing 2740 UK lupus patients who were matched 1:4 with controls from the UK Clinical Practice Research Datalink between 1999 and 2012. (Citation source http://buff.ly/1nJWKIT)
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ANA Negative Lupus Nephritis - Does it Exist?
A recent report from the Mayo Clinic describes a 49 year-old patient with lupus nephritis who presented with new-onset hypertension, edema, arthritis, serositis and leukocytoclastic vasculitis, and who later developed glomerulonephritis and nephrotic syndrome.
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PML is Very Rare in Lupus
A systematic review of the literature was done to assess the relationship between immunosuppressive therapy, adult systemic lupus erythematosus (SLE) and the onset of progressive multifocal leukoencephalopathy.
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Ominous Outcomes for Lupus Nephritis
Hanly and coworkers have reported the results of a large lupus cohort study involving 1827 patients. SLE patients were enrolled early in their disease (0.5 years) and were followed for a mean of 4.6 years.
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Increasing Hospitalization Rates for Shingles in Lupus
An administrative claims study of lupus patients drawn from the United States National Inpatient Sample between 2000 to 2011, studied hospitalization rates related to bacteremia, pneumonia, opportunistic fungal infection, herpes zoster, cytomegalovirus, or pneumocystis pneumonia (P
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The Nine Lives of Hydroxychloroquine (Best of 2015)
Hydroxychloroquine is one of many medications frequently used in rheumatology practice.
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Preventing Hepatitis B Reactivation Due to Immunosuppressive Drug Treatments (Best of 2015)
Reactivation of hepatitis B virus infection can have devastating consequences, especially amongst those patients receiving immunosuppressive therapy.
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Should Lupus Patients Receive Influenza and Pneumococcal Vaccines? (Best of 2015)
Barry Waters, MD*: I have a 21 yr old lupus nephritis patient on mycophenolate, hydroxychloroquine and prednisone 40 mg per day.
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Herpes Zoster Increases the Risk of Stroke and MI
At the 2015 ACR annual meeting in San Francisco, Len Calabrese, DO, of the Cleveland Clinic, gave a plenary session talk linking "shingles" infection to an increased risk of CVA (
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Plasmacytoid Dendritic Cells Influences Early, But Not Established Lupus
The Journal of Immunology has published the findings of Virginia Tech researchers who have studied plasmacytoid dendritic cells and their ability to induce type I alpha interferon (IFN-α) in lupus. (Citation source: http://buff.ly/1MceeCl)
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