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COVID 19 Updates from RheumNow

ICYMI: 2020 Rheumatology Year in Review

2020 was historic, memorable and game-changing. Under the cloud of COVID-19, there were many significant and memorable advances and setbacks for the rheumatology world. In our accounting of most read articles for 2020, (not surprisingly) 17/20 were COVID-related.

RheumNow Podcast – As Good As I Ever Was (7.2.2021)

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.

RheumNow Podcast – Modern Treatment of RA Pregnancy (6.25.2021)

Dr. Jack Cush reviews this week’s news and journal reports featured on RheumNow.com.

Birthday Gatherings Increase COVID-19 Risk

How risky are family gatherings, birthday parties and informal social gatherings? A cross-sectional analysis suggests that birthdays may be associated with increased rates of COVID-19 infection within households where there is a high COVID-19 prevalence in the population. 

Treatment of MIS-C COVID in Kids

The NEJM has published results of a real-world efficacty trial showing that COVID infected children with the multisystem inflammatory syndrome in children (MIS-C) respond better to initial IVIG plus glucocorticoids (than IVIG alone) which was associated with less subsequent cardiovascular co

Tofacitinib Efficacy in COVID-19 Pneumonia

NEJM has published the results of an observational trial wherein tofacitinib given to patients hospitalized with Covid-19 pneumonia, was shown to significantly lower risk of death or respiratory failure.

EULAR 2021 – Day 4 Report

Lots of presentations on the last day; notably, the late breaking abstracts and others. Here are a few of my favorites from Day 4.

RheumNow Podcast - Best of EULAR 2021

Dr. Jack Cush reviews and highlights his favorite abstracts and presentations from last week's virtual EULAR 2021 meeting.

Israel provides COVID vaccine answers for rheumatic disease patients

The question as to how autoimmune rheumatic disease patients fare with the COVID vaccine is one being asked in rheumatologists’ offices everywhere this year, and at the EULAR 2021 Virtual Congress, data presented from Israel, one of the first countries to vaccinate on a br

COLCORONA: Protective Effect of Colchicine in COVID-19

Lancet Respiratory Medicine has reported the results of the COLCORONA trial, showing that in patients with PCR-confirmed COVID-19 infection, colchicine led to a significantly lower rate of death or hospital admission from COVID.

RheumNow Podcast – Heart, Lung & Liver (5.28.2021)

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.

Methotrexate Impairs COVID Vax Response

MedPage Today

One-third of patients with immune-mediated inflammatory diseases being treated with methotrexate showed attenuated responses to the COVID-19 vaccine, researchers reported.

Social

PMR/GCA patients: should you be worried about how well your COVID vaccine worked? Actually, post-two vaccines, pretty good Ab (&cellular) response, esp if not on MTX/PNL>10 Glad to see our PMR/GCA pts protected @VasculitisUMCG @SleenYannick @ElisabethBrouw3 #EULAR2022 @RheumNow https://t.co/9vy0W4ojOF
David Liew @drdavidliew ( View Tweet )
1 year 11 months ago
The third SARS-CoV-2 vaccine in IMID (RA, SpA, PsA, UC, CD) patients on immunosuppression improves the serologic response follow the first two vaccine doses and allowed them to close the gap compared to the two-dose vaccinated controls #EULAR2022 @RheumNow OP0192 Jyssum et al

Dr. Antoni Chan @synovialjoints ( View Tweet )

1 year 11 months ago
#EULAR2022 POS0256 by @CaoilfhionnMD, @DrLisaCS, @JuliePaikMD from @HopkinsRheum 10% of pts seronegative for COVID antibodies after vaccination ⭐️Risk factors: Non-white, J&J vaccine, MMF, RTX, GC, combination Rx, not-withholding peri-vaccination immunosuppression @Rheumnow https://t.co/Izd4QJlOWH
1 year 11 months ago
@Yuz6Yusof on breakthrough infections & severe #COVID in RTX treatment #EULAR2022 🦠Rate of mod/severe COVID infection comparable to pre-pandemic severe infection rate 💉High vaccination rate prevented severe disease 📊Consider #comorbidities & low IgG in risk-benefit assessment https://t.co/PGUVbHD7i2
Mrinalini Dey @DrMiniDey ( View Tweet )
1 year 11 months ago
#OP0247 #EULAR2022 Prof Mease analysed US Database (>1 million) pre- & post-Omicron using machine learning.Factors assoc with poor #COVID outcomes in IMID:age & comorbidities. Vaccination was protective. JAK-I and RTX increased risk weakly initially but not post-Omicron @RheumNow https://t.co/JCqTZvPgll
Md Yuzaiful Md Yusof @Yuz6Yusof ( View Tweet )
1 year 11 months ago
“Post-exertional fatigue is real (in #LongCovid), not their fault. Validate their symptoms. Pain is secondary.”- Dr. @LCalabreseDO #EULAR2022 @rheumnow https://t.co/hDvxJfb14f
TheDaoIndex @KDAO2011 ( View Tweet )
1 year 11 months ago
About 50% w/ #LongCOVID has persistent Sx's at 6 mos (fatigue, muscle weakness, insomnia, anxiety, depression, dyspnea). Risks: female, obesity &prior mechan ventilation. Interestingly, the pts have inc CRP levels. DLCO is low. – Prof R Mostard #EULAR2022 @rheumnow https://t.co/8jCEObjf5I
TheDaoIndex @KDAO2011 ( View Tweet )
1 year 11 months ago
Don’t forget about the benefits of vaccines for diseases other than #COVID19 – Dr. K Hyrich #EULAR2022 @rheumnow https://t.co/86e93ugoBQ
TheDaoIndex @KDAO2011 ( View Tweet )
1 year 11 months ago
#EULAR2022 "The mRNA vaccines are simple to make." - Saul Faust The key step is encapsulation in lipid to allow for take up by cell. 💉💉💉 @RheumNow https://t.co/T2ZxF6bLV5
1 year 11 months ago
In people without SLE who have severe COVID19 infection, autoAb against IFN-1 assc w/increased mortality Prof T Dorner #EULAR2022 @rheumnow https://t.co/nt2gACUtkL
TheDaoIndex @KDAO2011 ( View Tweet )
1 year 11 months ago