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Type 2 SLE: Insights from a Biopsychosocial Framework

Many of the common symptoms of lupus - fatigue, nociplastic pain, brain fog - can be invisible and difficult to measure. These symptoms can often co-occur with impaired sleep, depression and anxiety. They can be debilitating, and result in poor quality of life.

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Rules on Mycophenolate Use in SLE

Dr. Diane Kamen. a rheumatologist and lupologist from the Medical University of South Carolina in Charleston, South Carolina, discusses the use of mychophenolate in the management of systemic lupus. 

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SLE Treatment Landscape: Abundance or Overload?

Imagine a world where the multiple drugs in Phase 2 and 3 trials actually get approved, and we get access to them? I know you may be thinking that I am overly optimistic, but there are so many drugs in development in lupus that we may have true difficulty choosing what to use.

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Do SGLT2 and GLP-1 therapies have a role in Lupus?

Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2i) and Glucagon-like peptide-1 receptor agonists (GLP1-RA) were initially developed as glucose-lowering agents for the treatment of Type 2 Diabetes.

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Belimumab in SLE with Mucocutaneous or Vasculitis Findings

A post hoc analysis of a belimumab (BEL) inn systemic lupus erythematosus (SLE) study showed lupus mucocutaneous and vasculitic  manifestations improve with BEL and standard care.
 
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Valves Gone Wild in SLE

Lupus valvulitis is a rare cardiac manifestation of active systemic lupus erythematosus (SLE) and is defined by inflammation of one or more cardiac valves.

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50 Year Perspective on Lupus

Hello, I'm Dafna Gladman, a rheumatologist from the University of Toronto. I'm actually speaking to you from Toronto this morning. I'm going to talk about what we've learned from an observational cohort study that was started in Toronto by Dr. Murray Urowitz in 1970.

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Contemporary lupus nephritis treatment

The Lupus 2025 congress brought together world SLE thought leaders.

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2025 ACR Guideline for the Treatment of SLE

The ACR has released its 2025 Systemic Lupus Erythematosus (SLE) treatment guidelines and consensus-based good practice statements, applicable to children and adults with SLE. 

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How Living With Childhood-Onset Lupus Impacts Mental Health

What We Know and Where We Are Going

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IMPACT Study - Certolizumab Efficacy in APS Pregnancies

A pilot trial assessed the safety and value of tumour necrosis factor α inhibitor treatment with certolizumab in patients with high-risk pregnancies with antiphospholipid syndrome (APS).
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Diagnosing Neuropsychiatric SLE (5.23.2025)

Dr. Jack Cush reviews the news and journal reports from RheumNow.com - including views on the vagus nerve, NPSLE and CAR-T mania.

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Why Childhood SLE is More Severe than Adult SLE

Hi everyone. My name is Sangeeta Sule. I am the division director of pediatric rheumatology at Children's National Hospital in Washington, DC. I'm here today to talk about why pediatric lupus patients have more severe lupus than adult patients.

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Shifting the Management Paradigm for SLE and Lupus Nephritis

The paradigm for treating patients with systemic lupus erythematosus (SLE) is rapidly shifting and our patients will surely benefit with improved outcomes. 

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Moving Targets in Lupus and Lupus Trials

Clinical Trial Data Quality is a Moving Target

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Is Lupus Just a B Cell Disorder?

I'm very happy to give you some insights entitled, “Is Lupus a B-Cell Disorder”. I will review some aspects, mainly pros and cons, but at the end you may forgive me, I will escape a little bit from a clear yes or no.

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Steroids in Lupus Nephritis: No Free Lunch

Hello, I'm Mike Putman, I'm Assistant Professor of Medicine at the Medical College of Wisconsin in Milwaukee, Wisconsin. Today I'm here to talk with you about steroids in lupus nephritis. The impetus for this is the 2024 ACR guideline for the management of lupus nephritis. 

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Biologics in Pregnancy Patients With Autoimmune Disease

A large cohort, claims data study shows that among pregnant women receiving biologic therapies for autoimmune conditions, 72% continued their biologics pregnancy, more so among inflammatory bowel disease (IBD) patients than those with rheumatoid arthritis (RA), psoriasis (PsO) or psoriatic arthri

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Panacea of Prednisone & Cannabis (5.16.2025)

Dr. Jack Cush reviews the news, journal and regulatory reports from this week on RheumNow.com.  Interesting trends and results with prednisone in lupus, cannabis in RA and opioid deaths too!

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SLE, Antiphospholipid Antibodies, and the Placenta

It is well established that women with systemic lupus erythematosus (SLE) are at increased risk for adverse pregnancy outcomes, including preeclampsia, preterm birth, and pregnancy loss. However, the pathophysiologic mechanisms driving these complications are not yet fully understood.

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