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RheumNow Week in Review – 26 August 2016

Aug 26, 2016 3:22 pm

Dr. Jack Cush reviews news and journal reports from the past week on RheumNow.com.

  1. Japanese study 345 RA pts shows sustained high CRP levels associated with increased risk of CKD (~20%) https://t.co/VWOxuHOCDl
  2. Gout patients have a 17% increased risk of fracture (limbs & spine). Interestingly allopurinol use lowers risk http://buff.ly/2c1V2kI
  3. SPIRIT-P1 Study published in Lancet; Ixekizumab (Taltz), IL-17 inhibitor, better than Placebo, but same as Humira at 24wks in psoriatic arthritis outcomes; but Taltz superior to Humira at Psoriasis outcomes. https://t.co/mVZ0sMSHdX
  4. Hypotony (low intraocular pressure) is a sign of active, severe & usually symptomatic uveitis in Juvenile Arthritis https://t.co/qJOAWPcPpW
  5. RCT of osteoporotic vertebral fractures (https://t.co/aIeKdXTU1C
  6. Risk factors for marginal ulcers in obesity gastric bypass surgery:Diabetes, Hx PUD, PPI & ASA use. But limited doses of. NSAIDs was not signif!cantly associated. PPI may be due to confounding by indication. https://t.co/9Ct4Xvmp2J
  7. DESIR early SpA Cohort - Structural progression is low (~5%) in early SpA; Sacroiliitis risk factors were B27, smoking & MRI SI inflammation https://t.co/MWsxlbb6lt
  8. Idiopathic Recurrent Pericarditis follows ~20% acute pericarditis; responds VERY well to IL-1 inhibition (anakinra) https://t.co/T28ggiTGyA
  9. Since FDA approval 2011, Benlystas uptake has been slow, but had $265 million in worldwide sales in 2014. https://t.co/hqViTE0PEs
  10. PsA have the same cancer & serious infx rates as non-PsA; but have more hematologic cancers & opportunistic infxns https://t.co/Mm9Ehpd19F
  11. Prior Cancer Patients May Safely Receive TNF Inhibitors or Rituximab
  12. Adalimumab Controls Non-Infectious Uveitis in VISUAL II Study
  13. Risk of Sepsis or Death Lower with Biologics in Rheumatoid Arthritis.
  14. EULAR 2016: Name that Country
Disclosures
The author has no conflicts of interest to disclose related to this subject

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