Mortality Risk Factors in Systemic Sclerosis

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A French cohort study of 625 systemic sclerosis (SStc) patients has found a significantly increased mortality risk that can be predicted by common clinical variables.

RheumNow Podcast – A Tofa Two-fer (4.12.19)

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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com

Dietary Supplements Fail to Reduce Mortality Risks

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An NIH funded prospective study has shown that the use of daily dietary supplements was not associated with a subsequent lowering of mortality risk.

An Autoimmune Diagnosis Alters Perceptions of Pregnancy and Lactation

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A study from UT Southwestern and the Baylor Research Institute examined the preceptions and practices of women with autoimmune or inflammatory rheumatic diseases (AIRD) noting that an AIRD diagnosis changed most womens future hopes and plans regarding pregnancy and lactation.

Chronic Kidney Disease Augments Gout Risks

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A population based cohort analysis shows that patients with incident gout and chronic kidney disease (CKD) have far worse outcomes than those without CKD.

ACR Position Statements on Drug Pricing and Step Therapy

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The American College of Rheumatology Committee on Rheumatologic Care has released new drug pricing and step therapy position statements that they hope legislators will consider as they continue to explore policy and regulatory options to make drugs more affordable and accessible.  

Increasing Prevalence and Consequences of Interstitial Lung Disease in RA

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Interstitial lung disease (ILD) has been a hot topic in numerous journals recently with reports of increasing incidence and links to disease activity.

FDA Approves Cimzia for Non-Radiographic Axial Spondyloarthritis

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The U.S. Food and Drug Administration today approved Cimzia (certolizumab pegol) injection for treatment of adults with a certain type of inflammatory arthritis called non-radiographic axial spondyloarthritis (nr-axSpA), with objective signs of inflammation.

For RA With COPD, Abatacept is Safe

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Patients with rheumatoid arthritis (RA) who also had chronic obstructive pulmonary disease (COPD) had no increased risk of serious respiratory complications when treated with abatacept (Orencia), a large claims-based analysis found.

Best of 2019 - Ups and Downs with Abatacept

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Two recent studies have examined the effect of starting abatacept upon the risk of serious hospitalized infections or cancer, showing divergent results from claims data analyses.

Presenting Features of Early SLE

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What clinical features best identify early systemic lupus erythematosus (SLE) patients from mimics?  A multicenter, multinational study aimed to evaluate manifestations at disease onset and to compare early SLE manifestations to those of diseases mimicking SLE.

Autoimmune Disease Clustering at ENDO 2019

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A twin registry database study was presented at the Endocrine Society's annual meeting (ENDO 2019) in New Orleans, showed that that having autoimmune disease significantly increases the risk of other autoimmune disorders and that autoimmune clustering was highest in Addison's disease and vit

Resistant Hypertension Common in SLE

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Rates of resistant hypertension were doubled among patients with systemic lupus erythematosus (SLE), significantly increasing their mortality risks, a retrospective single-center study found.

Improved Mortality Trends in Lupus Nephritis

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The mortality rate from end- stage renal disease (ESRD) in lupus nephritis (LN) patients has significantly decreased in the last decade.

Risky Painkillers Commonly Prescribed for Osteoarthritis

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Published guidelines warn that treating osteoarthritis (OA) with opioids and benzodiazepines can boost patients' risk of falling.

CRA Position Statement on Medical Cannabis Use

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Courtesy of the Canadian Rheumatology Association (CRA) website, here are consensus guidelines on medical cannabis use.

Rheumatology patients experience prevalent pain that is only modestly controlled with current treatment strategies.

RheumNow Podcast – You Owe Me a DEXA (3.15.19)

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Dr. Jack Cush reviews this week's news and highlights from RheumNow.com.

Lower TNF Inhibitor Persistence in Spondylitis

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A claims data analysis shows that only one-third of ankylosing spondylitis (AS) treated with tumor necrosis factor inhibitors (TNFi) therapy remain on their initial drug in the 2 years post initiation.

First Line IL-1 Inhibition in Systemic JIA

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First-line treatment of systemic juvenile idiopathic arthritis (JIA) with anakinra (Kineret) was highly effective as monotherapy, minimizing the need for glucocorticoids, a single-center prospective study found.

2018 Swedish Guidelines for Giant Cell Arteritis Treatment

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The Swedish Society of Rheumatology has developed evidence-based guidelines for the management of giant cell arteritis (GCA) with a focus on the appropriate use of corticosteroids and tocilizumab.