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RheumNow Podcast – Rheumatology Burnout (1.29.2021)

Jan 28, 2021 10:25 pm

Dr. Jack Cush reviews this past week's journal articles and news features on

  1. Protective Effects of Colchicine in Non-Hospitalized COVID-19 A press release from the Montreal Heart Institute has announced that the COLCORONA clinical trial has provided evidence of the protective effect of colchicine.

  2. Vaccine Rollout: Fed has delivered about 44.4 million Vax doses to states (~24 mill doses given). Estimated 6% (19.9 mill) have had one vax dose and 1% (3.5 mill) 2 doses. 2.7 of 3 million elderly in nursing homes long-term-care have recv >= 1 vax dose .

  3. QD Clinic - Dadgummit, Where's Waldo's COVID Vaccine?

  4. Among 335 AAV pts, 18% had venous thromboembolism (VTE). The incidence rate of AAV-related VTE was 2.4/100 PYs and was higher in the first 3 months post–AAV diagnosis (20.4/100 PY) and decreased over time. Age & BVAS were predictive of VTE.

  5. The risk of RA was studied in cohort of 14,463 endometriosis pts. RA risk was higher in those w/ endometriosis [adjusted HR 1.75), and also w/ age ≥45 years (adj HR 1.50) or with autoimmune disease (adj HR 6.99).

  6. tREACH trial of 120 early arthritis pts shows risk factors for persistence are predictive: Seropositivity, polyarthritis (>4), erosive Dz, high ESR/CRP. Those w/ 0, 1 and ≥2 risk factors had a 61%, 32% and 30% (respective) chance of drug free remission.

  7. Systematic review (39 studies 152K patients) of comorbidities in Psoriatic arthritis; most common were HTN 34%, metabolic syndr 29%, obesity 27%, hyperlipidaemia 24% &CV Dz 19%. Comorbid pts: more severe dz, worse QOL & more drug discontinuation

  8. 13 patients with SAPHO syndrome with nail lesions and palmoplantar pustulosis were treated wtih tofacitinib with significant improvement in nail scores (58-77%), psoriasis scores, QOL, DQLI and acute phase reactants.

  9. Osteitis in Systemic Sclerosis is UNCOMMON. French study of 48 pts shows 54% w/ osteitis beneath digital tip ulcers. Pain (75%), erythema (73%), warmth (73%) & 65% had high CRP. X‐ray, CT‐scans or MR. Antibiotics were 1st line therapy.

  10. Lupus Nephritis Despite Low Level Proteinuria

  11. Voclosporin FDA Approved for Lupus Nephritis

  12. Rheumatologists Rank 2nd in Physician Burnout

The author has received compensation as an advisor or consultant on this subject

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