RheumNow Podcast – Rheumatology Burnout (1.29.2021) Save

Dr. Jack Cush reviews this past week's journal articles and news features on RheumNow.com.

1. Protective Effects of Colchicine in Non-Hospitalized COVID-19 A press release from the Montreal Heart Institute has announced that the COLCORONA clinical trial has provided evidence of the protective effect of colchicine. https://t.co/B65RGButgm

2. Vaccine Rollout: Fed has delivered about 44.4 million Vax doses to states (~24 mill doses given). Estimated 6% (19.9 mill) have had one vax dose and 1% (3.5 mill) 2 doses. 2.7 of 3 million elderly in nursing homes long-term-care have recv >= 1 vax dose .https://t.co/HaoIRP4Uoo

3. QD Clinic - Dadgummit, Where's Waldo's COVID Vaccine?

4. Among 335 AAV pts, 18% had venous thromboembolism (VTE). The incidence rate of AAV-related VTE was 2.4/100 PYs and was higher in the first 3 months post–AAV diagnosis (20.4/100 PY) and decreased over time. Age & BVAS were predictive of VTE. https://t.co/Arb2gk27B7

5. The risk of RA was studied in cohort of 14,463 endometriosis pts. RA risk was higher in those w/ endometriosis [adjusted HR 1.75), and also w/ age ≥45 years (adj HR 1.50) or with autoimmune disease (adj HR 6.99). https://t.co/lDjSgLxXfV

6. tREACH trial of 120 early arthritis pts shows risk factors for persistence are predictive: Seropositivity, polyarthritis (>4), erosive Dz, high ESR/CRP. Those w/ 0, 1 and ≥2 risk factors had a 61%, 32% and 30% (respective) chance of drug free remission.https://t.co/AsCLGu4Vye

7. Systematic review (39 studies 152K patients) of comorbidities in Psoriatic arthritis; most common were HTN 34%, metabolic syndr 29%, obesity 27%, hyperlipidaemia 24% &CV Dz 19%. Comorbid pts: more severe dz, worse QOL & more drug discontinuation https://t.co/VxyYlPltDc

8. 13 patients with SAPHO syndrome with nail lesions and palmoplantar pustulosis were treated wtih tofacitinib with significant improvement in nail scores (58-77%), psoriasis scores, QOL, DQLI and acute phase reactants.https://t.co/J8yB4pRHS1

9. Osteitis in Systemic Sclerosis is UNCOMMON. French study of 48 pts shows 54% w/ osteitis beneath digital tip ulcers. Pain (75%), erythema (73%), warmth (73%) & 65% had high CRP. X‐ray, CT‐scans or MR. Antibiotics were 1st line therapy. https://t.co/o58gwq2SCC

10. Lupus Nephritis Despite Low Level Proteinuria

11. Voclosporin FDA Approved for Lupus Nephritis

12. Rheumatologists Rank 2nd in Physician Burnout