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COVID 19 Updates from RheumNow

Infections & Lupus (10.28.2022)

Dr. Jack Cush discusses the news and journal reports from the past week on RheumNow. This week more lupus nephritis, more drug induced lupus and more lupus infections that may kill. 

ACR Award Winners (10.21.2022)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. Highlighted discussion of implantable stimulators, urine proteomics and gut-immune responses to Prevotella in RA.

Vaccination Cut Long COVID Risk for Rheum Patients

MedPage Today

Patients with rheumatologic conditions who developed breakthrough COVID-19 infection after vaccination were less likely to suffer long-term symptoms than unvaccinated but otherwise similar patients, researchers said.

RheumNow Podcast – “That’s Not My Name” (10.7.2022)

Dr. Jack Cush goes off on "Untitling" (not using proper names/titles) in the clinic, in addition to reports on rheumatologist salaries, new drugs in phase 1-3 development and the range of COVID-19 MSK symptoms -- all from the past week on RheumNow.com.

Great and Not So Great (9.30.2022)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

COVID-19 Arthropathy and Myalgia

An online survey of random COVID-19 infected persons shows that arthralgia and myalgia are common consequences to COVID-19 infection.

2022 Lasker Award Winners

EurekAlert!

The Lasker Foundation has announced the winners of its 2022 Lasker Awards: Richard O. Hynes (Massachusetts Institute of Technology), Erkki Ruoslahti (Sanford Burnham Prebys) and Timothy A.

Heavy Metal Rheumatology (9.23.2022)

Thanks to all of you for your kind comments and great reviews of our weekly podcast.

COVID Outcomes in Dermatomyositis

A retrospective study of dermatomyositis (DM) patients with COVID-19, shows that DM patients without comorbidities fair well (with regard to mortality and hospitalisation).

Does Fibromyalgia Need B12? (9.9.2022)

Can we predict the bad outcomes? Like when ITP evolves into SLE; or when psoriasis will develop arthritis; or if Sjogren's will develop lymphoma? Let's dive in and review these journal reports and this past week's news from RheumNow.com.

Goofy But True

Dr. Jack Cush discusses declining survival rates in the USA, FDA approvals of new COVID subvariant boosters and other odd and possibly true new research reports from the past week on RheumNow.com.

FDA Approves BA.4 and BA.5 Omicron COVID Booster Vaccines

Today the FDA authorized the updated Omicron subvariant (BA.4 and BA.5) COVID-19 booster shots manufactured by Pfizer and Moderna; with an anticipated ship/start date of early September 2022. The BA.5 subvariant accounts for more than 88% of U.S. infections.

Social

Factors associated with higher prevalence of post COVID-19 condition include female sex, age, asthma, diabetes, hypertension, number of symptoms in the acute phase and possible mechanisms causing the syndrome, Mayssam Nehme, COVID-19, #EULAR2023 https://t.co/IzHEQqfPb1
Dr. Antoni Chan @synovialjoints ( View Tweet )
8 months 3 weeks ago
Reflections on COVID-19 and autoimmunity: post-vaccination autoimmunity is not specific to COVID-19, autoimmunity is not autoimmune disease, the large numbers may result in the perception of increased occurrence of autoimmunity, Schulze-Koops H, COVID-19, #EULAR2023 @RheumNow https://t.co/Rm9OEWrBzo
Dr. Antoni Chan @synovialjoints ( View Tweet )
8 months 3 weeks ago
Factors related to having a flare of arthritis during COVID-19 include female gender, higher disease activity, no DMARD at time of vaccination. Stopping DMARDs need to be weighed up against risk of flares, Pedro Machado, COVID-19 #EULAR2023 @RheumNow https://t.co/3sd32tF2kW
Dr. Antoni Chan @synovialjoints ( View Tweet )
8 months 3 weeks ago
Lit review of 2236 articles found only 28 w/ Post-COVID autoimmune Dx (64% F; age 51 yrs) - that included 11 (39) IIM (w/ 4 DM); 7 (25%) SLE; 4 (14%) anti-synthetase syndrome; 4 (14%) SSc; 1 lupus/MCTD overlap. Mean onset 23.7 d post COVID https://t.co/jtRaqIBGH1 https://t.co/WilcRFNAL9
Dr. John Cush @RheumNow ( View Tweet )
9 months 1 week ago
in 2022 COVID slid from the #3 to the #4 cause of death in USA, accounting for nearly a quarter million deaths, a 47 percent decrease from the 462,193 Covid-related deaths in 2021. Most COVID deaths occured in the first few mos of 2022 https://t.co/qervCp0P87 https://t.co/WN7DvsFhNC
Dr. John Cush @RheumNow ( View Tweet )
9 months 2 weeks ago
COVID had a significant effect on mental health of inflammatory rheumatic Dz (IRDs) pts. UK NHS survey of 639 IRD (70% RA, 16% PsA) saw 40% w/ mod/severe pandemic impact on physical & mental health; 29% w/ depression, 22% anxiety; affecting Women>males https://t.co/kcAwa2Lks2 https://t.co/R6tk2aOrGQ
Dr. John Cush @RheumNow ( View Tweet )
10 months 1 week ago
Industry Payments to Rheums Dropped During COVID Having their clinics shut down and patients staying away during the COVID-19 pandemic was bad enough for physicians' finances, but now a new study finds that payments from industry dried up as well. https://t.co/jsxw23tTyY https://t.co/5PiaRpiSa4
Dr. John Cush @RheumNow ( View Tweet )
10 months 2 weeks ago

Anakinra Phase 2/3 study in severe hosp. COVID-19 pts (5/20-3/21) w/ pneumonia & hyperinflammation (incr levels IL-6, ferritin, CRP, LDH). 179 pt Rx w/ ANA or SOC - d15 need for Mech ventilation was 77% ANAK v 86% SoC (NS; RR 0.90; 0.77-1.04) https://t.co/CFcI1qTsU2 https://t.co/wAj4pHN5Dh

Dr. John Cush @RheumNow ( View Tweet )
10 months 2 weeks ago
Paxlovid (Nirmatrelvir-Ritonavir) should be used w/in 5d of COVID Sxs onset. Drug interactions include: steroids, anticoagulants (Eliquis, Xarelto, warfarin), Flomax, Calcium channel blockers, benzodiazepines. https://t.co/VZpS1z3OGR https://t.co/hR6JAJ3BBO
Dr. John Cush @RheumNow ( View Tweet )
10 months 3 weeks ago
Autoimmune-Rheum Dz (AIRD) flares occur in 10% w/ COVID vaccination, esp in pts w/ comorbidities, autoimmune morbidities & mental health disorders & Moderna vaccine. 3453 AIRD pts who recv Vax 9.5-11.3% had clinical flares (Arthritis 62% & fatigue 59%) https://t.co/C0WA2Znixl https://t.co/vXzL8XR7kd
Dr. John Cush @RheumNow ( View Tweet )
10 months 3 weeks ago