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RheumNow Podcast – Pandemic Numbers (4.3.20)

Apr 03, 2020 3:00 am

Dr. Jack Cush reviews the news on COVID-19 and FDA actions this past week. Be sure to check out:

  1. COVID-19 Town Hall for Rheumatologists
  2. ID Specialist Dr. Jade Le answers questions about COVID - PPE, Masks, Package deliveries, Managing rheum Pts w/ suspicious Sxs, Testing and consulting ID. Watch here>> or listen on iTunes or here>>
  3. RheumNow interviews Dr @philipcrobinson about the rapid growth/impact of the COVID-Global Rheumatology Alliance Registry & how you can join and enroll your rheum patients with suspected COVID. or podcast here>
  4. The US deaths doubling time is 2.6 days. Which = 100,000 deaths by April 11th and 200,000 by April 14th (you're hearing underestimates) Unless something gives via flattening. Here's @BMcNoldy's updated best-fit. We all need to hope this shifts downward. Soon.
  5. 3/29 There are 122,653 cases of COVID-19 in the US, with 2112 deaths. On CNN Sunday, Dr. Anthony Fauci said there could be over 100,000 deaths and millions of people infected - but added "Dont hold me to that", this is "such a moving target." (as of 4/3/20 there are over 5000 deaths in the USA)
  6. Here are my thoughts about the irrational use of HCQ during the COVID-19 pandemic. Let's hit pause, develop a rational strategy to study benefit, and prevent harm to people with rheumatic disease. Thanks to @alhkim @rheum_covid
  7. Should Rheum & Derm pts stop biological during #Covid_19? Likely not as a flare may put pts at risk of seeking medical attention or adding steroids. The #outbreak won’t be over for awhile. Ontario Rheum Assoc says take meds unless fever/SOB. J Article review @RheumNow @RheumInfo
  8. Corona infections are trending down in China, with no new cases reported in Hubei province, for the sixth consecutive day on Sunday.
  9. Lilly's Taltz (ixekizumab) Receives U.S. FDA Approval for the Treatment of Pediatric Patients with Moderate to Severe Plaque Psoriasis -
  10. FDA Requests Removal of All Ranitidine (Zantac) from the Market - based on its investigation of the contaminant N-Nitrosodimethylamine (NDMA) in ranitidine; the impurity in ranitidine products increases over time, esp at higher temps
  11. The FDA has approved the investigational use of COVID-19 Convalescent Plasma - allowing clinicians to use as single-patient emergency Investigational New Drug Applications (INDs) - Must apply w/ form 3926
  12. On 3/31/20 the FDA granted "emergency use authorization" for the use of chloroquine and hydroxychloroquine in the treatment of COVID-19, noting circumstances exist justifying the authorization of emergency use of these agents
  13. FDA fact sheet for patients and parent/caregivers regarding the emergency use autorization (EUA) of hydroxychloroquine sulfate for the treatment of COVID-19 in certain hospitalized patients
  14. Be careful, QT prolongation is a known effect of chloroquine and hydroxychloroquine. Could be worsened when used with azithromycin. Death and problems reported from France.
  15. CDC: Impact of Underlying Health Conditions Among COVID-19 Patients  
  16. Universal Masking for COVID?  


The author has no conflicts of interest to disclose related to this subject

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