54K Peptic Ulcers Annually (12.13.2024) Save

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com

1. 2024 Match results are in - Rheumatology- 287 matched, 98%: Top 6: 1. Cardi 99.8% 2. Cardio EP 98% 3. Endocrinology 98.4 % 4. GI 99.6% 5. Heme/Onc 99.7% 6. Rheum 99% https://t.co/PBuQPIQaqo
2. Way Behind in Pediatric Rheumatology While adult rheumatology fellowships have surged in popularity and become quite competitive, more than half of pediatric rheumatology fellowship positions went unfilled in 2024, according to the National Resident Matching Program (NRMP).… https://t.co/O03bA0xWL8
3. Chikungunya marches on, at a cost A recent article from BMC Global Health suggests that between 2011 and 2020, the mosquito-borne disease chikungunya, has disabled millions and likely amassed close to $50 billion in healthcare and disability-related costs in 110 countries.… https://t.co/TnDObv1obT
4. Dengue fever, a mosquitoborne viral illness, is increasing worldwide; during 2024, approximately 13 million cases have been reported in the Americas. 2010–2024, a total of 15,077 (38.6%) patients were hospitalized But the fatality rate is unchanged. 2023 DENV-3 recent outbreak in… https://t.co/BKrEmN4F6G
5. Comparison of 139 incident RA-ILD pts vs 686 controls followed for >12 mos showed Higher inflammation (ESR OR 1.86, CRP OR 1.55) [not DAS, TJC, SJC] were signif assoc w/ ILD risk. Data from RABBIT - German Biologics register https://t.co/MMvfgVQfaL
6. Review of IgA Vasculitis (Henoch–Schönlein Purpura) - the freq of glomerulonephritis is higher in adults than children and tends to present more severely. Rx w/ 1st line steroids, Other agents: Colchicine, dapsone, MTX (Minor dz), CsA, tacrolimus, MMF (steroid sparing)… https://t.co/Dv2MY7WA2U
7. Small, suspended, post COVID randomized trial, guselkumab failed to show efficacy at reducing proteinuria in 33 SLE pts. Wk24 results, 56% placebo vs. 35% GUS for primary end point., No differences in secondary outcomes or adverse events https://t.co/27imkXkbUn
8. In US, peptic ulcer disease affects 1% of population w/ ~ 54 000admitted to hospital annually w/ bleeding peptic ulcers. But only 10% of PUD pts present w/ upper abdominal pain. Prime causes are Helicobacter pylori infection (42%) & NSAID use (36%) https://t.co/0VvA7lI0MQ
9. CorEvitas registry study of 1823 psoriatic arthritis pts found that 11.1% fulfilled the fibromyalgia definition and 20.6% fulfilled the widespread pain definition. Factors assoc w/ FM: female, depression, anxiety, impaired function, BMI & #of comorbidities.… https://t.co/rBZwUxQ8yw
10. Metabolic syndrome assoc w/ with response rates in #RA (CDAI MCID OR 0.6), on or off TNFi. Adipokines were associated with metabolic syndrome but were not associated with clinical responses. Data from CERTAIN cohort & CorEvitas registry https://t.co/YH44iTwYTr
11. Lancet forecasts that in Australia 5.4 million will have arthritis 2040, a 31% increase 4.1 mill in 2025. Included 3.2 w/ OA, ~750K w/ RA, & 8500 w/ JIA. OA incr in males from 6.3% to 7% (2040). & 10.8 to 12.2% in F. RA will grow from 1.56 to 1.75% in males and 2.6 to 2.9% in… https://t.co/6DM0ZLlZ05
12. Although there is a bidirectional relationship betw pain and sleep, Sleep impairment more strongly predicts pain than pain does sleep. Addressing sleep disturbances is crucial, as it is linked to higher levels of disability, depression, pain-related catastrophizing.… https://t.co/MaW706l6rn
13. Infertility linked to post-childbrith onset of systemic autoimmune disease Women who experience infertility but do not use fertility treatments have a higher risk of developing a group of conditions called systemic autoimmune rheumatic diseases (SARD) in the nine years after a… https://t.co/NJf44KJ2Hc
14. Outcome of Pain in Hand Osteoarthritis 
15. Drug-Free Remission in Giant Cell Arteritis is Uncommon 
16. Join us at RheumNow Live February 8 & 9 in Dallas, TX! Our incredible meeting will feature speakers like: Rheumatology Power Trio: Exploring RA Management in Older Adults, AI Innovations, and Multimorbidity Strategies Una Makris, MD, MSc Jeff Curtis, MD, MS, MPH Bryant… https://t.co/7WawLxwBLP